PROTOCOL FOR THE ELECTROENCEPHALOGRAPHY GUIDANCE OF ANESTHESIA TO ALLEVIATE GERIATRIC SYNDROMES (ENGAGES-CANADA) STUDY: A PRAGMATIC, RANDOMIZED CLINICAL TRIAL [VERSION 2; PEER REVIEW: 2 APPROVED]

Protocol for the electroencephalography guidance of anesthesia to alleviate geriatric syndromes (ENGAGES-Canada) study: A pragmatic, randomized clinical trial [version 2; peer review: 2 approved]

Background: There is some evidence that electroencephalography guidance of ASTRAGALUS general anesthesia can decrease postoperative delirium after non-cardiac surgery.There is limited evidence in this regard for cardiac surgery.A suppressed electroencephalogram pattern, occurring with deep anesthesia, is associated with increased incidence of posto

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Non-coding RNAs change their expression profile after Retinoid induced differentiation of the promyelocytic cell line NB4

Abstract Background The importance of non-coding RNAs (ncRNAs) as fine regulators of eukaryotic gene expression has emerged by several studies focusing on microRNAs (miRNAs).miRNAs represent a newly discovered family of non coding-RNAs.They are thought to be crucial players of human hematopoiesis and related tumorigenesis and to represent a potenti

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